Saw Wiki
Eric's Test Antidote Safe Room Magnum Eyehole

You all possess the combination to the safe. Think hard. The numbers are in the back of your mind. The clue to their order can be found over the rainbow.
— Jigsaw alerting the victims about how to get the combination of the safe

The Antidote Safe Room is a trap, as well as a fictional location, from the Saw franchise. It was a minor location in Saw II and Saw V.

Design and Function

The Antidote Safe Room was a room located on the ground floor of the Nerve Gas House and was the starting point of a deadly game set up by John Kramer, better known as the Jigsaw Killer, and his apprentice, Detective Mark Hoffman. The room itself was in a dilapidated state with the windows being blocked by metal barricades in order to prevent its inmates from leaving the house. Additionally the heavy metal door to the room was locked and secured by a booby trap on the other side. A deadly nerve agent, similar to the Sarin Gas used during the Tokyo subway attacks on March 20, 1995, was carried into the room through a small ventilation shaft. This would cause the inmates who were breathing in the gas to die after approximately two hours unless they managed to find syringes with the antidote hidden all around the house. One was located inside a large safe in the middle of the room. Under the safe was a hidden trapdoor leading down to an underground tunnel network. Unknown to the victims, they had numbers in different colours written on their necks. The order in which the colours appeared on the rainbow was also the same order in which the numbers had to be entered in order to open the safe. A tape containing the instructions and clues for the game as well as a key to the trapdoor and a warning message were hidden inside a hollow space behind a brick wall. Everything that happened in the room was recorded by a camera. (Saw II, V)



During his series of murders, John Kramer eventually targeted seven people for a big game taking place in the Nerve Gas House: Jonas Singer, his manager Gus Colyard, the prostitute Addison Corday, the drug dealer Xavier Chavez, Laura Hunter, Obi Tate and Daniel Matthews. Additionally Amanda Young, who had become Jigsaw's second apprentice after having survived a test on her own, was among the prisoners and played as a victim as well primarily to observe the game and make sure that the rules were followed. These people had a connection which initially none of them knew about. Daniel's father, the corrupt detective Eric Matthews, once innocently framed the other six people for crimes they didn't commit by faking the evidences.

Hoffman takes Obi to the Nerve Gas House

To accelerate their proceedings John hired Obi Tate to help him with the abduction of Daniel Matthews and the other five people while he prepared the traps for each one of them. When all of them were abducted and brought to the Nerve Gas House, Mark Hoffman abducted Obi as well and took him to the same location, making him the last test subject of the game. All of them were unconscious and lay on the floor of the Antidote Safe Room. John placed the tape recorder containing the instructions behind a wall and helped Hoffman to install the booby trap connected to the lock of the room's door. Having finished all of their preparations John and Hoffman left the room and locked the door. (Saw II, V)

The Nerve Gas House

Greetings and welcome. I trust that you are all wondering where you are. I can assure you that while your location is not important, what these walls offer you is important: salvation, if you earn it. Three hours from now, the door to this house will open. Unfortunately, you only have two hours to live. Right now, you are breathing in a deadly nerve agent. You've been breathing it since you arrived here. Those of you familiar with the Tokyo subway attacks will know its devastating effects on the human body. The only way to overcome it and walk out that door is to find an antidote. Several are hidden around this house. One is inside the safe in front of you. You all possess the combination to the safe. Think hard. The numbers are in the back of your mind. The clue to their order can be found over the rainbow. Once you realize what you all have in common, you will gain a better understanding of why you're here. X marks the spot for that clue, so look carefully. Let the game begin.
— The Nerve Gas House Instruction Tape[src]

Shortly afterwards, the prisoners woke up and were immediately frightened by the situation. Jonas tried to wake up Amanda, who was the last one who was still unconscious, while Addison yelled that someone should open the door. Xavier sarcastically commented that no one was listening, to which Laura responded that someone was and pointed at a camera. However Daniel, who squatted in a corner out of fear, said that those kinds of cameras didn't record sounds. The group's concerns grew worse when Gus suddenly started to panic. Gus talked about a movie he had seen about a man who had been trapped in a room for nine years, which frightened the others, especially Laura, and caused a discussion with Xavier. They were quickly interrupted when Addison heard a ticking on the other side of the door. However before they could find out what it was, Amanda suddenly woke up. Playing her role as another victim, she behaved as if she were in a panic and searched the room until she finally found the instruction tape as well as the key and the message which warned them not to use the key to open any door in the room.

Laura and Xavier witness Gus' death

The tape told them that they were all breathing in a deadly nerve gas since the moment they arrived in the house. While the doors would open after three hours the gas would already kill them after two hours. In order to survive the prisoners had to find syringes with the antidote which were hidden in the house with one of them being in the safe. Additionally Jigsaw told them that they all had a connection and told them that the clue to this connection was marked with a "X". After listening to the tape Xavier grabbed the key. Amanda begged him to listen to the message which warned them not to use the key to open any door in the room. However he refused to do so and tried to open the door which activated the booby trap and caused a magnum on the other side to go off and shoot Gus Colyard right in the eye. While the other prisoners panicked, Jonas demanded Amanda to tell him how she knew about the tape. She then told them about Jigsaw and his games and therefore also revealed that she had survived one of his tests before.

Amanda tries to remove the gun

As they now knew the amount of danger in their situation, the group began to search the whole room. Daniel picked up Gus' jacket from the floor and used it to cover the latter's mutilated head. Moments later the door of the room finally opened. Jonas was shocked when he saw the magnum trap which had killed Gus. Amanda tried to remove the gun and take it with her, albeit unsuccessful. Therefore the group left the room behind and made their way to the entrance hall. (Saw II)


Xavier discovers the number in Gus' neck

As time went by, the prisoners' desperation worsened as they hadn't managed to get one of the antidotes yet. Eventually Xavier, who had separated from the others, returned to the Safe Room. Upon entering, he accidentally pulled the jacket covering Gus' corpse away. When he wanted to put it back he suddenly discovered a red "2" written on the back of Gus' neck and therefore finally realized the meaning of Jigsaw's clues from the instruction tape. Moments later, Jonas entered the room. Due to the effects of the nerve gas he spit blood and threw up on the floor. In an attempt to convince Xavier to work together, he told him that they had more in common than he thought. Furthermore he told him that he had enemies that would go after his family if they wouldn't get their hands on him. However Xavier wasn't interested and instead told Jonas to turn around so he could see the number on the back of his neck. When he pulled out a knife from his waistband, the two of them engaged in a brutal fight during which Xavier was heavily injured when Jonas kicked him right in the face. Unfortunately Jonas lost the upper hand when the effects of the gas forced him on his knees. Embracing his opportunity, Xavier grabbed a nail-studded baseball bat which he had found earlier and brutally smashed Jonas' head. Stunned by the blow, Jonas turned around and tried to speak, but ultimately fell dead before he could mutter his finals words. When he was dead, Xavier checked the number in his neck, which was a yellow "16". After that he went for the other prisoners and shouted for them, claiming he had found a way out.

Xavier checks Laura's number

Following Jonas' death, Xavier went to the basement where Obi had been killed after being trapped in a furnace. However as the flames only burned his lower body, Xavier was still able to find his number, a green "11". While he checked Obi's corpse for the number, Amanda reentered the Antidote Safe Room after separating from the others and found Jonas' corpse. Alerted by this, she reunited with Daniel and told him they had to leave. Shortly afterwards Xavier also found the corpse of Laura, whose dead body lay on the floor in a hallway after succumbing to the gas. He turned her over onto her belly in order to see her number: a purple "8". Moments later, Amanda and Daniel crossed his path. He told them not to run away. Despite this they tried to flee and ran to the first room while Xavier pursued them. However he stumbled when he heard Addison screaming for help.

Xavier checks Addison's number

Upon following her voice, Xavier found Addison in one of the other rooms. Unfortunately her hands were trapped in a large glass box by several razor blades which prevented her from pulling them back. Frightened and in tears, Addison begged Xavier to help her. Xavier stepped closer to her and told her that everything was okay. However he was merely interested in the number written on her neck, a blue "9". After obtaining the number, Xavier slowly walked out of the room and closed the door behind him, leaving Addison for death. (Saw II)


After leaving Addison, Xavier took up his pursuit again and reached the Safe Room where Amanda and Daniel were hiding. When he tried to break through the door Amanda grabbed the nail-studded baseball bat which was still stuck in Jonas' skull and used it to jam the door. Due to the odd shape of the puddle of blood emerging from his smashed head Amanda realized there was a hidden trapdoor on the floor. With Daniel's help she managed to push the heavy safe away and unlocked the trapdoor with the key found in the beginning of the game which was in Jonas' pocket at this point.

Xavier cuts his neck

Only seconds after Daniel and Amanda went through the trapdoor and found the underground tunnels underneath the house, Xavier managed to open the door and continued to pursue them. Full of fear Amanda and Daniel ran away and followed the tunnel until they found another door. When they entered the room and turned on the lights the room was revealed to be a grimy industrial bathroom where they found the decomposed corpses of Adam Stanheight and Zep Hindle, two other victims of Jigsaw's deadly games who died several months ago already. As there was no other way to escape the room Daniel decided to sham being dead. Just a few seconds later Xavier entered the room. When Amanda told him Daniel was gone he told her that all he wanted from her was a number written on her and Daniel's neck as those numbers were the combination to the safe which contained one of the antidotes. Amanda reminded him that he would still need her as she was the only person left who could tell him about his own number. However instead of asking her for help Xavier eventually cut off the skin from his neck with a knife he previously found in the basement while Amanda was watching in horror. When he was done he approached her but was killed by Daniel who suddenly jumped up and sliced his throat with the hacksaw previously used by Lawrence Gordon to cut off his own foot. When Xavier died in front of them, Amanda started screaming.

However as she and Daniel were the only survivors left in the house the time for the next part of her and John's plan had come. Amanda subdued Daniel and injected him with the antidote from the safe. Afterwards she took his unconscious body with her and brought him to the Wilson Steel Plant, where John was already waiting for her to arrive. (Saw II)


The room was found approximately two days later when Daniel's father, Eric, reached the Nerve Gas House as he had been provided with the recordings of the game by Jigsaw and thought that his son was still trapped inside. Upon entering the room he found the remains of Gus and Jonas, who already showed obvious signs of decomposition, as well as the syringe used by Amanda to cure Daniel from the nerve gas. Shortly afterwards he also found the corpse of Xavier in the bathroom. However as he was abducted only minutes later, he wasn't able to tell his colleagues about the house's location. (Saw II)

Following the end of the game and the abduction of Eric, Detective Mark Hoffman returned to the Nerve Gas House, where he disposed of the traps as well as the corpses of the other prisoners. Additionally, he renovated the entire building and even refurnished it, giving it the appearance of an average residential house. (Saw V)


  • Given the numbers revealed, the combination to the safe would be 2-?-16-11-9-8/?-?/8, the orange number was never revealed and it's not clear whether Laura's number is indigo or violet.
  • Since there are 7 colors of the rainbow (red, orange, yellow, green, blue, indigo, and violet) and 8 players, 1 of the players may not have had number written on their neck; it's likely that this is either Daniel or Amanda, so Xavier didn't need to chase them, since he would have had the last number.